Description

Hydroxyethyl β-Cyclodextrin is a chemically modified derivative of β-cyclodextrin, engineered to enhance solubility and stability for advanced formulation challenges. This versatile excipient is critical for improving the bioavailability and delivery of poorly soluble active ingredients. It is an essential material for pharmaceutical development, cosmetic science, and food technology, where precise molecular encapsulation is required.

Application

• Pharmaceutical Solubilization & Stabilization: Used as a complexing agent to enhance the aqueous solubility, stability, and bioavailability of poorly soluble APIs in injectable and oral formulations.
• Drug Delivery Systems: A key component in the development of controlled-release systems, nasal sprays, and ophthalmic solutions.
• Cosmetic & Personal Care: Functions as a carrier for fragrances, vitamins, and active ingredients in creams, lotions, and serums to improve skin penetration and stability.
• Food & Flavor Industry: Employed to encapsulate, protect, and mask flavors, colors, and nutrients, controlling their release and improving shelf-life.
• Analytical Chemistry & Research: Utilized in chiral separation techniques (e.g., capillary electrophoresis, chromatography) and as a molecular host in laboratory studies.
• Agrochemical Formulations: Enhances the solubility and efficacy of pesticides and herbicides, improving their application and environmental profile.

Basic Information

Product Name	Hydroxyethyl β-Cyclodextrin
CAS No.	128446-32-2
Molecular Formula	(C6H10O5)7·(C2H4O)n
Molecular Weight	~1135 g/mol (base) + substitution-dependent
Synonyms	2-Hydroxyethyl-β-cyclodextrin; HE-β-CD; Hydroxyethyl-β-cyclodextrin; HEBCD; β-Cyclodextrin hydroxyethyl ether; (2-Hydroxyethyl)-β-cyclodextrin; Hydroxyethylated β-cyclodextrin; β-Cyclodextrin, 2-hydroxyethyl ethers
EINECS	Contact for details

Quality Control

Our Hydroxyethyl β-Cyclodextrin is manufactured under a strict quality management system. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and food-grade applications. A comprehensive Certificate of Analysis (COA) documenting identity, assay, substitution degree, residual solvents, and microbiological quality is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Degree of Substitution (DS)	To customer specification
Water Content (KF)	≤ 10.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Microbiological Enumeration	Meets Ph. Eur. specifications

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.