Description

Ranitidinebismuthcitrate CAS NO 128345-62-0 is a coordination complex of ranitidine, bismuth, and citrate, designed to leverage the therapeutic properties of its components. This compound is primarily valued for its dual-action role in gastrointestinal therapy, combining acid suppression with mucosal protection. It is a critical active pharmaceutical ingredient (API) for manufacturers developing advanced treatments for peptic ulcers and related gastric disorders, serving the global pharmaceutical and research sectors.

Application

• Primary Active Pharmaceutical Ingredient (API) in anti-ulcer medications.
• Key component in combination therapies for Helicobacter pylori eradication.
• Research and development of novel gastroprotective drug formulations.
• Reference standard in analytical laboratories for quality control and method validation.
• Starting material for the synthesis of more complex pharmaceutical compounds.
• Use in preclinical and clinical studies investigating gastrointestinal pharmacology.

Basic Information

Item	Detail
Product Name	Ranitidinebismuthcitrate
CAS No.	128345-62-0
Molecular Formula	C13H22N4O3S • C6H8O7 • Bi
Molecular Weight	Contact for details
Synonyms	Ranitidine Bismuth Citrate; Ranitidine Bismuth Citrate Complex; Tritec (former brand name); Pylorid (former brand name); RBC; Bismuth Ranitidine Citrate; Ranitidine Bismuth Subcitrate; [N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine] Bismuth Citrate Complex
EINECS	Contact for details

Quality Control

Our Ranitidinebismuthcitrate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Production can be aligned with cGMP guidelines upon request to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Bismuth Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.