Description

Cyclopropanecarbonyl Chloride, 2-Chloro-2-Fluoro-1-Methyl- (9Ci) CAS NO 128230-83-1 is a high-purity, halogenated cyclopropane derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents on the cyclopropane ring, makes it a valuable electrophilic reagent for introducing functionalized cyclopropyl groups into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for constructing complex molecules with cyclopropane motifs in drug discovery and development programs.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, where the cyclopropane ring can enhance biological activity and stability.
• Material Science Research: Serves as a precursor for specialty monomers or polymers with tailored properties.
• Fluorine Chemistry: Exploited in methodologies for introducing fluorine atoms into organic frameworks, a common strategy in modern medicinal chemistry.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed coupling reactions to form carbon-carbon bonds.
• Academic & Contract Research: Employed in universities and CROs for methodological studies and the synthesis of novel chemical entities.

Basic Information

Product Name	Cyclopropanecarbonyl Chloride, 2-Chloro-2-Fluoro-1-Methyl- (9Ci)
CAS No.	128230-83-1
Molecular Formula	C5H5Cl2FO
Molecular Weight	170.99 g/mol
Synonyms	2-Chloro-2-fluoro-1-methylcyclopropanecarbonyl chloride; 1-Methyl-2-chloro-2-fluorocyclopropanecarboxylic acid chloride; 2-Chloro-2-fluoro-1-methylcyclopropanecarboxylic acid chloride; (2-Chloro-2-fluoro-1-methylcyclopropyl)carbonyl chloride; 2-Chloro-2-fluoro-1-methylcyclopropanecarbonyl chloride (9CI); 1-Methyl-2-chloro-2-fluorocyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarbonyl Chloride, 2-Chloro-2-Fluoro-1-Methyl- (9Ci) is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.