Description

3-(4-Azidobenzoyloxy)Diltiazem is a chemically modified derivative of the calcium channel blocker Diltiazem, designed for advanced research and development applications. This compound is particularly valuable as a photoaffinity labeling probe or a key intermediate in the synthesis of more complex bioactive molecules. It is primarily utilized by pharmaceutical researchers and contract development and manufacturing organizations (CDMOs) working on cardiovascular drug discovery and molecular biology studies.

Application

• Photoaffinity Labeling: A critical tool in biochemical research for identifying and studying drug-protein interactions and receptor binding sites.
• Proteomics Research: Used to map biological pathways and understand the mechanisms of action of calcium channel modulators.
• Pharmaceutical Intermediate: Serves as a specialized building block in the synthesis of novel diltiazem analogs for preclinical evaluation.
• Bioconjugation: The azido group enables click chemistry reactions for attaching the diltiazem moiety to other molecules, surfaces, or carriers.
• Academic & Institutional Research: Employed in university and government labs for fundamental studies in cardiology and pharmacology.

Basic Information

Product Name	3-(4-Azidobenzoyloxy)Diltiazem
CAS No.	128127-11-7
Molecular Formula	C30H31N5O6S
Molecular Weight	589.66 g/mol
Synonyms	4-Azidobenzoyl Diltiazem; Diltiazem 4-Azidobenzoate; 3-[(4-Azidobenzoyl)oxy]-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; 3-(4-Azidobenzoyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; Diltiazem Azidobenzoate Derivative; Photoactivatable Diltiazem Derivative
EINECS	Contact for details

Quality Control

Our 3-(4-Azidobenzoyloxy)Diltiazem is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support research and development with materials suitable for use under GMP-like conditions for non-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, handling should be performed under subdued lighting conditions. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.