Description

(E)-(+/-)-2-Amino-4-Methyl-5-Phosphono-3-Pentenoic Acid Ethyl Ester is a specialized organophosphorus compound featuring a unique α,β-unsaturated amino acid ester structure. This molecular architecture makes it a valuable intermediate for the synthesis of bioactive molecules and complex ligands in pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists working in medicinal chemistry and catalysis. The compound's phosphonate group offers versatile reactivity for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of glutamate receptor modulators and other neuroactive compounds.
• Agrochemical Research: Precursor for developing novel herbicides and plant growth regulators that target specific enzymatic pathways.
• Chemical Biology Probe: Used in the design and synthesis of activity-based probes to study enzyme function and mechanism.
• Ligand Synthesis: Serves as a precursor for chelating agents and complex ligands used in catalysis and material science.
• Process Chemistry: An intermediate in the scalable synthesis of more complex, target active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for methodological development and studying phosphonate chemistry.

Basic Information

Product Name	(E)-(+/-)-2-Amino-4-Methyl-5-Phosphono-3-Pentenoic Acid Ethyl Ester
CAS No.	127910-32-1
Molecular Formula	C8H16NO5P
Molecular Weight	237.19 g/mol
Synonyms	Ethyl (E)-2-Amino-4-methyl-5-phosphono-3-pentenoate; 2-Amino-4-methyl-5-phosphono-3-pentenoic Acid Ethyl Ester; AMPA Ethyl Ester (Phosphonate analog); (E)-Ethyl 2-amino-4-methyl-5-phosphono-pent-3-enoate; DL-2-Amino-4-methyl-5-phosphono-3-pentenoic Acid Ethyl Ester; (±)-Ethyl 2-Amino-4-methyl-5-phosphono-3-pentenoate; Phosphonic acid, P-[(2E)-2-amino-4-methyl-3-pentenyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our (E)-(+/-)-2-Amino-4-Methyl-5-Phosphono-3-Pentenoic Acid Ethyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.