Description

7,8-Dihydro-7-Methyl-8-Thioxoguanosine is a chemically modified nucleoside derivative of guanosine, featuring a thioxo group at the 8-position. This specific modification makes it a valuable intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside analogs for therapeutic applications.
• Antiviral Research: Used in the development and study of potential antiviral compounds targeting viral polymerases.
• Oncology Research: Serves as a precursor or reference compound in the design of anticancer agents that interfere with DNA/RNA synthesis.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.
• Chemical Biology Probes: Utilized in the creation of probes to study cellular processes involving purine nucleosides.

Basic Information

Product Name	7,8-Dihydro-7-Methyl-8-Thioxoguanosine
CAS No.	127794-14-3
Molecular Formula	C11H15N5O5S
Molecular Weight	329.33 g/mol
Synonyms	7-Methyl-8-thioguanosine; 8-Thio-7-methylguanosine; 7-Methyl-8-mercaptoguanosine; 7,8-Dihydro-7-methyl-8-thioguanosine; 8-Thioxo-7-methylguanosine; 7-Methyl-8-sulfanylguanosine; Guanosine, 7,8-dihydro-7-methyl-8-thioxo-
EINECS	Contact for details

Quality Control

Our 7,8-Dihydro-7-Methyl-8-Thioxoguanosine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.