Description

Basifungin is a synthetic antifungal agent belonging to the echinocandin class, specifically identified by CAS NO 127785-64-2. This compound is valued for its potent activity against a broad spectrum of pathogenic fungi, particularly targeting the fungal cell wall synthesis. It is a critical intermediate and active pharmaceutical ingredient (API) essential for manufacturers in the pharmaceutical and biotechnology sectors developing advanced antifungal therapies. Its role is pivotal in addressing serious systemic fungal infections, supporting the production of both innovative and generic medicinal products.

Application

• Pharmaceutical API: Primary use as the active pharmaceutical ingredient in the formulation of injectable and topical antifungal medications.
• Antifungal Drug Development: Serves as a key intermediate in the research, development, and synthesis of new echinocandin-class antifungal drugs.
• Generic Drug Manufacturing: Essential for companies producing generic versions of established antifungal therapies containing basifungin.
• Biomedical Research: Used as a reference standard and tool compound in microbiological and pharmacological studies to investigate fungal resistance mechanisms and drug efficacy.
• Veterinary Pharmaceuticals: Applicable in the development of antifungal treatments for animal health.

Basic Information

Product Name	Basifungin
CAS No.	127785-64-2
Molecular Formula	C52H81N7O17
Molecular Weight	1052.24 g/mol
Synonyms	LY-303366; BSF; Echinocandin B; (4R,5R)-4,5-Dihydroxy-N2-[[4"-(pentyloxy)[1,1':4',1"-terphenyl]-4-yl]carbonyl]-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-trans-4-hydroxy-L-prolyl-(4R,5R)-4,5-dihydroxy-L-ornithine 1,6-Lactone; Antifungal agent LY 303366
EINECS	Contact for details

Quality Control

Our Basifungin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Specifications align with ICH guidelines, and identity, purity, and potency are verified by methods including HPLC, NMR, and MS. A Certificate of Analysis (COA) documenting all critical quality attributes is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Microbial Enumeration	Meets Ph. Eur. 2.6.12/ USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.