Description

5-Isoxazoleaceticacid,α-Amino-4,5-Dihydro-3-Methyl-,(R*,S*)-(9Ci) is a high-purity, non-racemic chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting neurological and metabolic pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides that leverage its unique isoxazole core structure for enhanced biological activity.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and proteomics research due to its amino acid-like functionality.
• Peptidomimetics: Acts as a constrained scaffold for designing peptide analogs with improved metabolic stability and receptor selectivity.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal complexation.
• Academic & Discovery Chemistry: A valuable reagent for methodological development in synthetic organic chemistry and library synthesis for high-throughput screening.

Basic Information

Product Name	5-Isoxazoleaceticacid,α-Amino-4,5-Dihydro-3-Methyl-,(R*,S*)-(9Ci)
CAS No.	127760-06-9
Molecular Formula	C6H8N2O3
Molecular Weight	156.14 g/mol
Synonyms	2-Amino-2-(4,5-dihydro-3-methyl-5-isoxazolyl)acetic acid; α-Amino-4,5-dihydro-3-methyl-5-isoxazoleacetic acid; (R*,S*)-2-Amino-2-(4,5-dihydro-3-methylisoxazol-5-yl)acetic acid; 5-Isoxazoleacetic acid, α-amino-4,5-dihydro-3-methyl-, (R*,S*)-; 127760-06-9; Amino-dihydro-methyl-isoxazoleacetic acid; NSC 339586
EINECS	Contact for details

Quality Control

Our 5-Isoxazoleaceticacid,α-Amino-4,5-Dihydro-3-Methyl-,(R*,S*)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure consistent quality and identity. Certificates of Analysis (COA) detailing purity, chiral composition, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.