Description

(3-Azidopropyl)Triphenylphosphonium Bromide is a specialized organophosphonium salt that serves as a versatile reagent in advanced organic synthesis. Its core value lies in its bifunctional structure, combining a reactive azide group with a triphenylphosphonium moiety, enabling its use in key transformations like Staudinger ligations and as a precursor for Wittig-type reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity building blocks for constructing complex molecular architectures.

Application

• Bioconjugation & Click Chemistry: A key reagent for Staudinger ligation, facilitating the site-specific labeling and modification of biomolecules such as proteins, peptides, and oligonucleotides.
• Advanced Organic Synthesis: Used as a phosphonium salt precursor for generating ylides in Wittig and related olefination reactions to form carbon-carbon double bonds.
• Pharmaceutical Intermediate: Employed in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs, particularly those requiring azide-functionalized scaffolds.
• Polymer & Materials Science: Acts as a functional monomer or cross-linking agent in the development of smart polymers, hydrogels, and surface-modified materials.
• Chemical Biology Probes: Integral for creating activity-based probes and affinity tags to study enzyme function and protein interactions within biological systems.
• Agrochemical Research: Utilized in the design and synthesis of new herbicide and pesticide candidates with tailored properties.

Basic Information

Product Name	(3-Azidopropyl)Triphenylphosphonium Bromide
CAS No.	127611-39-6
Molecular Formula	C21H21BrN3P
Molecular Weight	426.29 g/mol
Synonyms	3-Azidopropyltriphenylphosphonium Bromide; Triphenyl(3-azidopropyl)phosphonium Bromide; (3-Azidopropyl)triphenylphosphonium Bromide; Azidopropyl Triphenylphosphonium Bromide; N3(CH2)3PPh3Br; Phosphonium, (3-azidopropyl)triphenyl-, bromide (1:1); Phosphonium, triphenyl(3-azidopropyl)-, bromide
EINECS	Contact for details

Quality Control

Every batch of (3-Azidopropyl)Triphenylphosphonium Bromide is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including NMR, HPLC, and FTIR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the azide functionality, avoid contact with strong acids and heavy metal salts.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.