Description

2-Oxetanecarbonyl Chloride, 3,3-Diethyl- (9Ci) CAS NO 127565-53-1 is a specialized organic acid chloride derivative of a substituted oxetane, serving as a high-value building block in advanced synthetic chemistry. Its core value lies in introducing the strained, four-membered oxetane ring system, which is prized for modulating the physicochemical properties of target molecules in drug discovery and materials science. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty polymer industries seeking to enhance metabolic stability, solubility, or material characteristics.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly where the oxetane moiety is used to improve drug-like properties such as metabolic stability and solubility.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the oxetane ring can influence biological activity and environmental persistence.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating advanced polymers with unique thermal, mechanical, or optical properties.
• Ligand & Catalyst Development: Employed in the synthesis of complex ligands and organocatalysts for asymmetric synthesis and other specialized chemical transformations.
• Chemical Biology Probes: Useful for the preparation of molecular probes and tags used in proteomics and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Oxetanecarbonyl Chloride, 3,3-Diethyl- (9Ci)
CAS No.	127565-53-1
Molecular Formula	C8H13ClO2
Molecular Weight	176.64 g/mol
Synonyms	3,3-Diethyl-2-oxetanecarbonyl chloride; 3,3-Diethyloxetane-2-carbonyl chloride; 2-Oxetanecarbonyl chloride, 3,3-diethyl-; 3,3-Diethyloxetane-2-carboxylic acid chloride; 3,3-Diethyl-β-propiolactone-2-carbonyl chloride (obsolete); 127565-53-1; 3,3-Diethyl-2-oxetane carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Oxetanecarbonyl Chloride, 3,3-Diethyl- is produced and tested under strict quality management protocols to ensure consistency and purity for critical R&D and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical intermediates, ensuring traceability and documentation meet the stringent requirements of global regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening and protected from exposure to moisture and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.