Description

Benzoyl Fluoride, 3,4-Difluoro- (9Ci) CAS NO 127269-25-4 is a specialized fluorinated aromatic building block, a derivative of benzoyl fluoride with fluorine atoms at the 3 and 4 positions of the phenyl ring. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where the introduction of fluorine atoms is critical for modulating biological activity and metabolic stability. It is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate difluorobenzoyl motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of drugs containing difluorophenyl groups to enhance potency and pharmacokinetic properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Chemistry: Employed in the creation of specialty polymers and resins with enhanced thermal stability and chemical resistance.
• Organic Synthesis Reagent: Functions as an acylating agent or a fluorinated synthon in complex multi-step organic reactions under controlled conditions.
• Research & Development: Utilized in academic and industrial R&D labs for exploring new chemical entities and reaction methodologies involving fluorinated aromatics.

Basic Information

Product Name	Benzoyl Fluoride, 3,4-Difluoro- (9Ci)
CAS No.	127269-25-4
Molecular Formula	C7H3F3O
Molecular Weight	160.10 g/mol
Synonyms	3,4-Difluorobenzoyl Fluoride; 3,4-Difluorobenzoic Acid Fluoride; 3,4-Difluorobenzoyl Fluoride (9CI); 3,4-Difluorobenzoyl fluoride; 3,4-Difluorobenzoic fluoride; Benzoic acid, 3,4-difluoro-, fluoride; 127269-25-4
EINECS	Contact for details

Quality Control

Our Benzoyl Fluoride, 3,4-Difluoro- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, oxidizing agents, and moisture. Due to its nature as a strong acid/organic solvent and highly volatile compound, it is recommended to handle and store under an inert atmosphere (e.g., nitrogen) for long-term stability. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.