Description

1H-Pyrazole-4-Carbonyl Chloride, 3-Methyl-1-[(Methylamino)Carbonyl]- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality as a reactive carbonyl chloride and a protected pyrazole derivative, enabling the efficient construction of complex molecular architectures. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyrazole core is a common bioactive motif.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functional organic molecules for advanced materials, such as organic semiconductors or metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1H-Pyrazole-4-Carbonyl Chloride, 3-Methyl-1-[(Methylamino)Carbonyl]- (9Ci)
CAS No.	126675-00-1
Molecular Formula	C7H8ClN3O2
Molecular Weight	201.61 g/mol
Synonyms	3-Methyl-1-[(methylcarbamoyl)]-1H-pyrazole-4-carbonyl chloride; 1H-Pyrazole-4-carbonyl chloride, 3-methyl-1-[(methylamino)carbonyl]-; 3-Methyl-1-(N-methylcarbamoyl)-1H-pyrazole-4-carbonyl chloride; 1-(Methylcarbamoyl)-3-methyl-1H-pyrazole-4-carbonyl chloride; N-Methyl-3-methyl-1H-pyrazole-4-carboxamide-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-4-Carbonyl Chloride, 3-Methyl-1-[(Methylamino)Carbonyl]- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.