Description

1H-Pyrazole-5-Carbonyl Chloride, 3-Methoxy-1-Methyl- (9Ci) is a reactive acyl chloride derivative of a substituted pyrazole, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of more complex molecules, enabling the introduction of the pyrazole-carbonyl moiety under mild conditions. It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pyrazole core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and organic electronic materials that require specific heterocyclic architectures.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic and Industrial R&D: A valuable tool for method development and exploring new chemical spaces in both university laboratories and corporate R&D centers.

Basic Information

Item	Detail
Product Name	1H-Pyrazole-5-Carbonyl Chloride, 3-Methoxy-1-Methyl- (9Ci)
CAS No.	126674-99-5
Molecular Formula	C6H7ClN2O2
Molecular Weight	174.59 g/mol
Synonyms	3-Methoxy-1-methyl-1H-pyrazole-5-carbonyl chloride; 1-Methyl-3-methoxy-1H-pyrazole-5-carbonyl chloride; 5-Carbonyl chloride-3-methoxy-1-methylpyrazole; 3-Methoxy-1-methylpyrazole-5-carbonyl chloride; 1H-Pyrazole-5-carbonyl chloride, 3-methoxy-1-methyl-; 3-Methoxy-1-methyl-1H-pyrazole-5-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-5-Carbonyl Chloride, 3-Methoxy-1-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.