Description

(S)-1-(3,4-Difluorophenyl)Ethanol is a high-value chiral intermediate characterized by its specific stereochemistry and difluorophenyl moiety. This compound matters for its critical role in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), where its defined stereocenter ensures the desired biological activity and safety profile of the final drug product. It is primarily needed by research institutions and pharmaceutical manufacturers developing advanced therapeutics, particularly in the areas of central nervous system (CNS) agents and anti-infectives.

Application

• Key chiral building block for the synthesis of novel pharmaceutical compounds.
• Intermediate in the production of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Used in research and development for drug discovery programs, especially in medicinal chemistry.
• Precursor for ligands and catalysts used in asymmetric synthesis.
• Starting material for the development of agrochemicals and specialty fine chemicals.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	(S)-1-(3,4-Difluorophenyl)Ethanol
CAS No.	126534-40-5
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	(S)-1-(3,4-Difluorophenyl)ethanol; (S)-α-(3,4-Difluorophenyl)ethyl alcohol; (S)-3',4'-Difluoro-α-methylbenzenemethanol; (1S)-1-(3,4-Difluorophenyl)ethan-1-ol; (S)-(-)-1-(3,4-Difluorophenyl)ethanol; (S)-1-(3,4-Difluorophenyl)ethyl alcohol
EINECS	Contact for details

Quality Control

Our (S)-1-(3,4-Difluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.