Description

(1R)-1-(2,5-Difluorophenyl)Ethanol is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry and difluorophenyl moiety, which are critical for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the fluorinated aromatic structure enhances stability and bioavailability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of fluorinated liquid crystals or advanced polymers with specific optical or electronic properties.
• Reference Standard: Utilized as an analytical standard for quality control and method development in chiral separation techniques.

Basic Information

Product Name	(1R)-1-(2,5-Difluorophenyl)Ethanol
CAS No.	126534-37-0
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	(R)-1-(2,5-Difluorophenyl)ethanol; (1R)-1-(2,5-Difluorophenyl)ethan-1-ol; (R)-2,5-Difluoro-α-methylbenzyl alcohol; (+)-1-(2,5-Difluorophenyl)ethanol; (R)-(-)-1-(2,5-Difluorophenyl)ethanol; 2,5-Difluoro-α-methylbenzyl alcohol (R)-; 126534-37-0; (R)-1-(2,5-Difluorophenyl)ethyl alcohol
EINECS	Contact for details

Quality Control

Our (1R)-1-(2,5-Difluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assay and impurity profiling by HPLC, GC, and NMR, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.