Description

(1S)-1-(2,4-Difluorophenyl)Ethan-1-Ol CAS NO 126534-34-7 is a high-purity chiral alcohol intermediate, characterized by its specific (S)-configuration and difluorinated aromatic ring. This compound is a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs), where its defined stereochemistry is essential for biological activity. It is primarily required by pharmaceutical R&D and manufacturing sectors for the development of novel therapeutics, including antifungal and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the production of advanced Active Pharmaceutical Ingredients (APIs), particularly in antifungal and CNS drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides, leveraging the bioactivity of the difluorophenyl group.
• Material Science: Potential monomer or modifier in the synthesis of specialty polymers with unique optical or surface properties.
• Academic & Industrial R&D: Utilized in chemical research for methodology development and the exploration of new fluorinated compound libraries.

Basic Information

Product Name	(1S)-1-(2,4-Difluorophenyl)Ethan-1-Ol
CAS No.	126534-34-7
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	(S)-1-(2,4-Difluorophenyl)ethanol; (S)-α-(2,4-Difluorophenyl)ethyl alcohol; (1S)-1-(2,4-Difluorophenyl)ethanol; (S)-2,4-Difluoro-α-methylbenzyl alcohol; (S)-(-)-1-(2,4-Difluorophenyl)ethanol; (S)-1-(2,4-Difluorophenyl)ethyl alcohol; (S)-DFPE
EINECS	Contact for details

Quality Control

Our (1S)-1-(2,4-Difluorophenyl)Ethan-1-Ol is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available for every batch. Our quality commitment ensures consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.