Description

5'-Fluorosulfonylbenzoyldeoxyadenosine is a specialized, high-purity nucleoside derivative designed for advanced biochemical synthesis and research applications. This compound is valued for its unique reactive functional groups, which enable precise chemical modifications in complex molecular systems. It is primarily utilized by researchers and process chemists in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutics and diagnostic probes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of modified oligonucleotides and nucleotide-based prodrugs.
• Bioconjugation Reagent: Used for site-specific labeling and cross-linking of biomolecules such as proteins and nucleic acids.
• Proteomics Research: Serves as a reactive handle in activity-based protein profiling (ABPP) and enzyme inhibitor studies.
• Antiviral/Anticancer Agent Development: Investigated as a precursor for novel nucleoside analogs with potential therapeutic activity.
• Diagnostic Probe Synthesis: Employed in creating labeled nucleotides for imaging and detection assays.
• Chemical Biology Tool: Facilitates the study of enzyme mechanisms and nucleic acid interactions through covalent modification.

Basic Information

Product Name	5'-Fluorosulfonylbenzoyldeoxyadenosine
CAS No.	126463-19-2
Molecular Formula	C₁₇H₁₆FN₅O₆S
Molecular Weight	437.40 g/mol
Synonyms	5'-O-(4-Fluorosulfonylbenzoyl)deoxyadenosine; 5'-Deoxyadenosine-5'-(4-fluorosulfonylbenzoate); 4-Fluorosulfonylbenzoic Acid 5'-Deoxyadenosine Ester; 5'-FSB-dA; FSB-dA; 5'-(4-Fluorosulfonylbenzoyl)-2'-deoxyadenosine; 2'-Deoxyadenosine 5'-(4-fluorosulfonylbenzoate)
EINECS	Contact for details

Quality Control

Our 5'-Fluorosulfonylbenzoyldeoxyadenosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry. We support research and development with material that meets the stringent requirements for pharmaceutical intermediates and biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.