Description

3-Nitro-3-Deazauridine is a specialized nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a key intermediate and building block in the synthesis of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery programs. The unique structural modification of the uridine base makes it a valuable tool for probing biochemical pathways and developing targeted therapies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of experimental nucleoside-based antiviral drugs.
• Anticancer Research: Used in the development and screening of novel chemotherapeutic agents targeting DNA/RNA synthesis.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Medicinal Chemistry: A versatile building block for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry and biochemistry.

Basic Information

Product Name	3-Nitro-3-Deazauridine
CAS No.	126347-59-9
Molecular Formula	C9H11N3O7
Molecular Weight	273.20 g/mol
Synonyms	3-Nitro-3-deazauridine; 1-(β-D-Ribofuranosyl)-5-nitro-1H-pyridin-2-one; 5-Nitro-1-(β-D-ribofuranosyl)-1H-pyridin-2(1H)-one; 3-Deaza-3-nitrouridine; 5-Nitro-1-(β-D-ribofuranosyl)-2(1H)-pyridinone; 3-Nitro-3-deazauridine (3-NO2-3-DUrd); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-Nitro-3-Deazauridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. For cGMP-grade material or custom purity requirements, please contact our technical sales team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.