Description

Cyclohexanecarbonyl Chloride, 2-Methyl-4-Propyl-, (1Alpha,2Beta,4Beta)- (9Ci) is a high-purity, stereochemically defined acyl chloride derivative, serving as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry and reactive carbonyl chloride group make it invaluable for introducing the (1α,2β,4β)-2-methyl-4-propylcyclohexanecarbonyl moiety into target molecules with high regio- and stereoselectivity. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in constructing advanced, stereospecific active ingredients for herbicides, fungicides, and pesticides to enhance efficacy and environmental profile.
• Advanced Material Precursor: Employed in the synthesis of specialty polymers and liquid crystals where the specific cyclohexyl conformation imparts desired material properties.
• Asymmetric Catalysis Ligand Synthesis: Serves as a precursor for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing stereochemically pure aroma chemicals and musk analogs.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Cyclohexanecarbonyl Chloride, 2-Methyl-4-Propyl-, (1Alpha,2Beta,4Beta)- (9Ci)
CAS No.	126165-01-3
Molecular Formula	C11H19ClO
Molecular Weight	202.72 g/mol
Synonyms	(1α,2β,4β)-2-Methyl-4-propylcyclohexanecarbonyl chloride; (1R,2S,4S)-2-Methyl-4-propylcyclohexanecarbonyl chloride; trans-2-Methyl-4-propylcyclohexanecarbonyl chloride; 2-Methyl-4-propylcyclohexanecarboxylic acid chloride; (1Alpha,2Beta,4Beta)-2-Methyl-4-propyl-1-cyclohexanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonyl Chloride, 2-Methyl-4-Propyl-, (1Alpha,2Beta,4Beta)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and stereochemical integrity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing assay, enantiomeric/excess, and impurity profiles by HPLC, GC, and NMR are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Diastereomeric Purity (GC/HPLC)	≥ 98.0% de
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.