Description

11,18-Epoxy-2,3,18,21-Tetrahydroxypregnan-20-One is a high-purity, specialized steroid derivative with a complex polycyclic structure. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard for analytical and research purposes. It is primarily required by pharmaceutical R&D and fine chemical synthesis laboratories engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used for method development, validation, and quality control in analytical laboratories (HPLC, LC-MS).
• Biochemical Research: Investigated for its biological activity and potential interactions with steroid hormone receptors in preclinical studies.
• Process Chemistry: Employed in route scouting and optimization for the production of high-value steroid derivatives.
• Academic Research: Serves as a substrate or model compound in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	11,18-Epoxy-2,3,18,21-Tetrahydroxypregnan-20-One
CAS No.	126164-11-2
Molecular Formula	C21H30O6
Molecular Weight	378.46 g/mol
Synonyms	11,18-Epoxy-2,3,18,21-tetrahydroxypregn-20-one; 11,18-Epoxy-2,3,18,21-tetrahydroxypregnan-20-one; 11,18-Epoxy-2,3,18,21-tetrahydroxy-20-oxopregnane; 20-Oxo-11,18-epoxy-2,3,18,21-tetrahydroxypregnane; Pregnan-20-one, 11,18-epoxy-2,3,18,21-tetrahydroxy-; (5α)-11,18-Epoxy-2,3,18,21-tetrahydroxypregnan-20-one
EINECS	Contact for details

Quality Control

Our 11,18-Epoxy-2,3,18,21-Tetrahydroxypregnan-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.