Description

8-(Allyloxy)Guanosine is a chemically modified nucleoside derivative, specifically a guanosine analog with an allyloxy substituent at the 8-position. This structural modification makes it a valuable intermediate in organic synthesis and pharmaceutical research, particularly for the development of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in nucleoside chemistry and prodrug development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
• Probe Development: Serves as a precursor for fluorescent or affinity-labeled nucleosides used in diagnostic assays and molecular biology.
• Medicinal Chemistry: A crucial starting material for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized chemical libraries.

Basic Information

Product Name	8-(Allyloxy)Guanosine
CAS No.	126138-81-6
Molecular Formula	C13H17N5O5
Molecular Weight	323.31 g/mol
Synonyms	8-Allyloxyguanosine; Guanosine, 8-(allyloxy)-; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-(prop-2-enoxy)-3H-purin-6-one; 8-O-Allylguanosine; Allyl 8-guanosinyl ether
EINECS	Contact for details

Quality Control

Our 8-(Allyloxy)Guanosine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.