Description

2-Quinolinecarbonyl Chloride, 8-Hydroxy- (9Ci) is a specialized quinoline derivative that serves as a key reactive intermediate in advanced organic synthesis. Its value lies in the functional combination of an acid chloride group and a hydroxyl group on the quinoline scaffold, enabling precise molecular construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for building complex heterocyclic molecules and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting neurological and anti-infective pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand Synthesis: Serves as a precursor for creating complex chelating agents and catalysts used in metal-organic chemistry and catalysis.
• Fluorescent Probe Development: The quinoline core is utilized in constructing advanced molecular probes and sensors for biochemical and diagnostic applications.
• Material Science: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	2-Quinolinecarbonyl Chloride, 8-Hydroxy- (9Ci)
CAS No.	125686-91-1
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	8-Hydroxy-2-quinolinecarbonyl chloride; 8-Hydroxyquinoline-2-carboxylic acid chloride; 2-Carboxy-8-hydroxyquinoline chloride; 8-Hydroxyquinaldic acid chloride; 8-Hydroxy-2-quinolinecarboxylic acid chloride; 8-Hydroxy-2-quinolylcarbonyl chloride; 8-Hydroxyquinaldoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Quinolinecarbonyl Chloride, 8-Hydroxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.