Description

(3S)-1-Boc-3-Azido-Pyrrolidine is a high-purity chiral building block and key synthetic intermediate. This compound is of significant value for its dual functionality, featuring a Boc-protected amine and an azide group, enabling its use in click chemistry and peptide coupling reactions. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptidomimetics, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug candidates and bioactive molecules.
• Peptide Chemistry: Used in the construction of modified peptide backbones and peptidomimetics due to its pyrrolidine scaffold.
• Click Chemistry Substrate: The azide group readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and material science applications.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material for the preparation of enantiomerically pure compounds.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and probes for studying biological processes.
• Agrochemical Research: Employed in the discovery and development of novel, chiral agrochemicals.

Basic Information

Product Name	(3S)-1-Boc-3-Azido-Pyrrolidine
CAS No.	125552-56-9
Molecular Formula	C9H16N4O2
Molecular Weight	212.25 g/mol
Synonyms	1-Boc-3-azido-(S)-pyrrolidine; (S)-1-(tert-Butoxycarbonyl)-3-azidopyrrolidine; tert-Butyl (3S)-3-azidopyrrolidine-1-carboxylate; (S)-3-Azido-1-Boc-pyrrolidine; 1-Boc-3-azidopyrrolidine, (S)-; 3-Azido-1-N-Boc-(S)-pyrrolidine; (S)-1-Boc-3-azidopyrrolidine; (3S)-3-Azido-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is analyzed to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing results from HPLC, NMR, and specific rotation tests.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.