Description

9-(2',3'-Dihydroxycyclopentan-1'-Yl)Adenine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of nucleoside-based drugs targeting viral infections and proliferative diseases.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in R&D for developing therapeutics against DNA viruses, such as herpesviruses and hepatitis B virus (HBV).
• Oncology Research: Investigated as a potential precursor for chemotherapeutic agents that inhibit DNA replication in cancer cells.
• Biochemical Tool: Employed in enzymatic studies to understand substrate specificity and inhibition mechanisms of viral and human polymerases.
• Process Chemistry: Serves as a starting material for scale-up synthesis under Good Manufacturing Practice (GMP) conditions for clinical trial material.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and drug design.

Basic Information

Product Name	9-(2',3'-Dihydroxycyclopentan-1'-Yl)Adenine
CAS No.	125409-63-4
Molecular Formula	C15H19N5O2
Molecular Weight	301.35 g/mol
Synonyms	9-[(1S,2R,3S)-2,3-Dihydroxycyclopentyl]adenine; (1S,2R,3S)-9-(2,3-Dihydroxycyclopentyl)adenine; Cyclopentyladenine derivative; DHCA; cPr-D4A; 9-(2,3-Dihydroxycyclopent-1-yl)adenine; Adenine, 9-(2,3-dihydroxycyclopentyl)-; 125409-63-4
EINECS	Contact for details

Quality Control

Our 9-(2',3'-Dihydroxycyclopentan-1'-Yl)Adenine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.