Description

3'-Deoxy-3'-Fluoroaristeromycin is a fluorinated nucleoside analog, a derivative of the natural product aristeromycin. This compound is a valuable synthetic intermediate and research chemical, primarily utilized in the development of novel antiviral and anticancer agents. Its unique structure, featuring a fluorine atom at the 3'-position, makes it a critical building block for medicinal chemists and researchers in the pharmaceutical and biotechnology sectors. This product is supplied as a high-purity reference standard for advanced research and development.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate in the design and synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Studies: Used as a molecular probe to investigate enzyme mechanisms, particularly those involving S-adenosylhomocysteine (SAH) hydrolase and other nucleoside-processing enzymes.
• Antiviral Agent Development: Explored for its potential activity against a range of viruses due to its structural similarity to adenosine, which can interfere with viral replication.
• Medicinal Chemistry: Acts as a versatile scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties of nucleoside analogs.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis, chemical biology, and drug discovery pathways.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and quality assurance (QA) laboratories for method development and validation.

Basic Information

Product Name	3'-Deoxy-3'-Fluoroaristeromycin
CAS No.	125409-47-4
Molecular Formula	C12H16FN5O3
Molecular Weight	297.29 g/mol
Synonyms	3'-Deoxy-3'-fluoroneplanocin A; 3'-Fluoro-3'-deoxyaristeromycin; 9-[(1R,2S,3R,4R)-2,3-Dihydroxy-4-(hydroxymethyl)-1-fluorocyclopentyl]adenine; 3'-Fluoroneplanocin A; 3'-Fluoroaristeromycin; 3'-F-aristeromycin; Fluorinated Aristeromycin Derivative; Adenosine, 9-[2,3-dihydroxy-4-(hydroxymethyl)-1-fluorocyclopentyl]-
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'-Fluoroaristeromycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications. For custom purity grades or specific impurity profiles, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider desiccation and storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.