Description

2',3'-Dideoxy-3'-Fluoroaristeromycin is a fluorinated nucleoside analogue derived from the natural product aristeromycin. This compound matters as a valuable biochemical tool and synthetic intermediate, particularly for studying enzyme inhibition and antiviral mechanisms. It is primarily needed by researchers and developers in the pharmaceutical and biotechnology sectors for drug discovery programs targeting viral infections and for advanced organic synthesis.

Application

• Biochemical Research: Used as a potent inhibitor of S-adenosyl-L-homocysteine (SAH) hydrolase for studying methylation processes.
• Antiviral Agent Development: Serves as a key intermediate or reference standard in the synthesis and evaluation of novel antiviral compounds.
• Enzymology Studies: Employed to investigate the substrate specificity and catalytic mechanisms of nucleoside-processing enzymes.
• Medicinal Chemistry: Acts as a sophisticated building block for the structural modification and creation of nucleoside-based drug candidates.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in chemical biology and virology.

Basic Information

Product Name	2',3'-Dideoxy-3'-Fluoroaristeromycin
CAS No.	125356-68-5
Molecular Formula	C12H16FN5O3
Molecular Weight	297.29 g/mol
Synonyms	3'-Fluoro-2',3'-dideoxyaristeromycin; 9-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one; 3'-Fluoro-dd-aristeromycin; Fluorinated Aristeromycin Derivative; SAH Hydrolase Inhibitor; Nucleoside Analogue; Antiviral Nucleoside Intermediate
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxy-3'-Fluoroaristeromycin is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and assay is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.