Description

Bryophyllin B is a bioactive bufadienolide compound, a class of natural products known for their potent biological activities. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of cardiac glycosides and their therapeutic potential. It serves as an essential analytical standard for researchers and quality control laboratories in the pharmaceutical, biotechnology, and academic sectors requiring precise compound identification and quantification.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the identification, purity assessment, and quantification of bryophyllin B in raw materials and finished products.
• Bioactivity Research: Used in in vitro and in vivo studies to investigate its pharmacological properties, including potential effects on cardiac function and cytotoxicity against various cell lines.
• Natural Product Isolation & Analysis: Serves as a benchmark in the isolation, purification, and structural elucidation of related bufadienolides from plant sources like Kalanchoe species.
• Method Development & Validation: Essential for developing and validating analytical methods (e.g., HPLC, LC-MS) in quality control laboratories to ensure accuracy and reproducibility.
• Toxicological Studies: Employed in research to understand the compound's metabolic pathways, toxicity profile, and safe exposure levels.

Basic Information

Product Name	Bryophyllin B
CAS No.	125339-13-1
Molecular Formula	C24H32O5
Molecular Weight	400.51 g/mol
Synonyms	Bryophyllin B; 3β,5β,14β-Trihydroxy-19-oxobufa-20,22-dienolide; 3β,5β,14β-Trihydroxy-19-oxo-20,22-dienolide; Bufadienolide from Kalanchoe; 19-Oxobryophyllin B; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Bryophyllin B is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.