Description

3'-Deoxy-3'-Fluoro-Xyloguanosine is a fluorinated nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate and a potential building block for novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of modified nucleic acids and nucleotide-based drugs. The product is supplied with a focus on high purity and batch-to-batch consistency to support critical research and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used in studies investigating the structure-activity relationships of modified nucleosides and their interaction with viral polymerases or cellular enzymes.
• Pro-drug Development: Acts as a precursor molecule in the design and synthesis of nucleotide pro-drugs to enhance bioavailability and targeting.
• Antiviral Agent Research: Investigated for its potential activity against a range of viral pathogens due to its modified sugar moiety.
• Labeled Compound Synthesis: Can be used as a starting material for the preparation of isotopically labeled (e.g., 13C, 15N) guanosine derivatives for metabolic tracing studies.
• Academic Research: Employed in university and institutional labs for fundamental research in medicinal chemistry and chemical biology.

Basic Information

Product Name	3'-Deoxy-3'-Fluoro-Xyloguanosine
CAS No.	125291-15-8
Molecular Formula	C10H12FN5O4
Molecular Weight	285.23 g/mol
Synonyms	3'-Deoxy-3'-fluoroxylanosine; 9-[(3-Deoxy-3-fluoro-β-D-xylofuranosyl)]guanine; 3'-Fluoro-3'-deoxyxyloguanosine; 3'-F-dXG; 2-Amino-9-[(3-deoxy-3-fluoro-β-D-xylofuranosyl)]-1,9-dihydro-6H-purin-6-one; Guanosine, 3'-deoxy-3'-fluoro-, β-D-xylo- isomer; 125291-15-8
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'-Fluoro-Xyloguanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality commitment supports applications requiring high-purity reference standards and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.