Description

4-Thiazolidinecarboxylic Acid, 3-(Chlorocarbonyl)-, Methyl Ester, (R)- (9Ci) is a high-purity chiral building block and key synthetic intermediate. This compound matters for its role in constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel APIs, particularly for drugs targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Peptidomimetic Research: Serves as a constrained scaffold in medicinal chemistry for designing protease inhibitors and other bioactive peptide analogs.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis and organometallic complexes.
• Fine Chemical Production: A versatile intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: Essential for exploratory synthetic chemistry in both academic laboratories and corporate R&D divisions.

Basic Information

Product Name	4-Thiazolidinecarboxylic Acid, 3-(Chlorocarbonyl)-, Methyl Ester, (R)- (9Ci)
CAS No.	125278-26-4
Molecular Formula	C6H8ClNO3S
Molecular Weight	209.65 g/mol
Synonyms	(R)-3-(Chlorocarbonyl)-4-thiazolidinecarboxylic acid methyl ester; Methyl (R)-3-(chlorocarbonyl)thiazolidine-4-carboxylate; (R)-Methyl 3-(chlorocarbonyl)thiazolidine-4-carboxylate; (4R)-3-(Chlorocarbonyl)-1,3-thiazolidine-4-carboxylic acid methyl ester; 4-Thiazolidinecarboxylic acid, 3-(chlorocarbonyl)-, methyl ester, (R)-; (R)-Thiazolidine-4-carboxylic acid, 3-(chlorocarbonyl)-, methyl ester; 125278-26-4; (R)-3-Carboxy-4-thiazolidinecarbonyl chloride methyl ester
EINECS	Contact for details

Quality Control

Our 4-Thiazolidinecarboxylic Acid, 3-(Chlorocarbonyl)-, Methyl Ester, (R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.