Description

2'-Deoxyribofuranosyl-1-Deazapurine is a specialized nucleoside analog, a key building block in advanced chemical synthesis. This compound is valued for its role in the research and development of novel therapeutic agents and diagnostic tools. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on nucleoside chemistry, antiviral studies, and oligonucleotide synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand biological pathways involving purine metabolism.
• Oligonucleotide Synthesis: Acts as a modified nucleoside monomer for the solid-phase synthesis of oligonucleotides with altered properties for research and diagnostic applications.
• Antiviral Agent Development: Investigated for its potential activity against viral polymerases, making it relevant for developing treatments for viral infections.
• Chemical Biology Probes: Employed in the design of molecular probes to study DNA/RNA interactions and enzyme mechanisms.
• Academic & Industrial R&D: A fundamental reagent for exploring new chemical entities in medicinal chemistry and drug discovery programs.

Basic Information

Product Name	2'-Deoxyribofuranosyl-1-Deazapurine
CAS No.	125178-07-6
Molecular Formula	C11H13N3O4
Molecular Weight	251.24 g/mol
Synonyms	1-Deaza-2'-deoxyadenosine; 1-Deaza-2'-deoxyadenosine; 1-Deazapurine-2'-deoxyriboside; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-1-deazapurine; 2'-Deoxy-1-deazapurine riboside; 1-Deazapurine deoxyribonucleoside; 1-Deaza-dA
EINECS	Contact for details

Quality Control

Our 2'-Deoxyribofuranosyl-1-Deazapurine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.