Description

1-Piperidinecarbonylchloride,4-Acetyl-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its piperidine core structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: Employed in the design and synthesis of peptidomimetics and protease inhibitors due to its carbonyl chloride and acetyl functionalities.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the creation of activity-based probes and other tools for studying enzyme function and biological pathways.

Basic Information

Product Name	1-Piperidinecarbonylchloride,4-Acetyl-(9Ci)
CAS No.	125094-85-1
Molecular Formula	C8H12ClNO2
Molecular Weight	189.64 g/mol
Synonyms	4-Acetylpiperidine-1-carbonyl chloride; 1-(Chlorocarbonyl)-4-acetylpiperidine; 4-Acetyl-1-piperidinecarbonyl chloride; 4-Acetylpiperidine-1-carboxylic acid chloride; NSC 339063; 4-Acetylpiperidine-1-carbonylchloride; 4-Acetyl-1-piperidinecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarbonylchloride,4-Acetyl-(9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development, ensuring data integrity and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.