Description

5-Isoxazolecarbonyl Chloride, 3-Phenyl- (9Ci) is a versatile and highly reactive chemical building block, specifically an acid chloride derivative of a phenyl-substituted isoxazole. This compound is critical for the efficient synthesis of amides and esters, enabling the rapid introduction of the 3-phenylisoxazole-5-carbonyl moiety into more complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazole heterocycle.
• Chemical Biology Probe Development: Serves as a reagent for labeling proteins or modifying biomolecules to study biological pathways and protein function.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with unique thermal or optical properties.
• Custom Synthesis & Contract Manufacturing: Essential for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.

Basic Information

Item	Detail
Product Name	5-Isoxazolecarbonyl Chloride, 3-Phenyl- (9Ci)
CAS No.	124953-60-2
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	3-Phenylisoxazole-5-carbonyl chloride; 3-Phenyl-1,2-oxazole-5-carbonyl chloride; 5-Carboxy-3-phenylisoxazole chloride; 3-Phenyl-5-isoxazolecarboxylic acid chloride; 3-Phenylisoxazolyl-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Isoxazolecarbonyl Chloride, 3-Phenyl- (9Ci) is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.