Description

8-Azabicyclo[3.2.1]Octane-3-Carbonyl Chloride, 8-Methyl- (9Ci) is a high-value, specialized organic intermediate featuring a complex bicyclic structure with a reactive acid chloride functional group. This compound is critical for pharmaceutical research and development, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce its unique tropane-derived scaffold into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex molecules, particularly in the development of central nervous system (CNS) active drugs, receptor antagonists, and other bioactive compounds.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, where its bicyclic structure can contribute to novel modes of action.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation, labeling probes, or in the synthesis of molecular tools for studying biological systems.
• Material Science: Potential precursor for specialty polymers, ligands for catalysis, or advanced organic frameworks due to its rigid, three-dimensional structure.
• Academic & Contract Research: Serves as a valuable reagent in academic laboratories and CROs (Contract Research Organizations) for methodological development and exploratory synthesis.

Basic Information

Item	Detail
Product Name	8-Azabicyclo[3.2.1]Octane-3-Carbonyl Chloride, 8-Methyl- (9Ci)
CAS No.	124946-97-0
Molecular Formula	C9H12ClNO
Molecular Weight	185.65 g/mol
Synonyms	8-Methyl-8-azabicyclo[3.2.1]octane-3-carbonyl chloride; 3-(Chlorocarbonyl)-8-methyl-8-azabicyclo[3.2.1]octane; Tropane-3-carbonyl chloride, 8-methyl-; 8-Methyltropane-3-carbonyl chloride; 8-Methyl-3-tropanecarbonyl chloride; Nortropine-3-carbonyl chloride, N-methyl-; 8-Methyl-8-azabicyclo[3.2.1]oct-3-ylcarbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 8-Azabicyclo[3.2.1]Octane-3-Carbonyl Chloride, 8-Methyl- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.