Description

4-Isoxazolecarbonyl Chloride, 5-Cyclopropyl- (9Ci) is a highly reactive and versatile acid chloride derivative of a cyclopropyl-substituted isoxazole. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the 5-cyclopropylisoxazole-4-carbonyl moiety into target molecules. It is primarily needed by pharmaceutical and agrochemical research and development teams for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the isoxazole scaffold is valued for its bioactivity.
• Chemical Research & Development: Employed in academic and industrial labs for method development and the synthesis of novel heterocyclic compounds.
• Peptide Mimetics & Conjugation: The reactive carbonyl chloride group facilitates amide bond formation, useful in creating peptide analogs or bioconjugates.
• Material Science Precursor: Can act as a monomer or functionalization agent in the synthesis of specialized polymers with unique properties.

Basic Information

Product Name	4-Isoxazolecarbonyl Chloride, 5-Cyclopropyl- (9Ci)
CAS No.	124845-05-2
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	5-Cyclopropylisoxazole-4-carbonyl chloride; 5-Cyclopropyl-1,2-oxazole-4-carbonyl chloride; 4-Carbonyl chloride-5-cyclopropylisoxazole; 5-Cyclopropyl-4-isoxazolecarbonyl chloride; Cyclopropanecarbonyl chloride, 2-isoxazolyl-; (5-Cyclopropyl-1,2-oxazol-4-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Isoxazolecarbonyl Chloride, 5-Cyclopropyl- (9Ci) is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.