Description

2H-1,2-Oxazine-2-Carbonylchloride,3,6-Dihydro-5-(1-Methylethyl)-(9Ci) is a specialized heterocyclic building block featuring a reactive carbonyl chloride group. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and agrochemicals. The CAS number for this compound is 124739-89-5.

Application

This reactive intermediate serves as a versatile synthon in advanced organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the oxazine core can impart specific biological activity.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes (ABPs) or affinity tags due to its electrophilic carbonyl chloride moiety.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the research of specialty polymers with unique properties.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and the exploration of new chemical spaces.

Basic Information

Product Name	2H-1,2-Oxazine-2-Carbonylchloride,3,6-Dihydro-5-(1-Methylethyl)-(9Ci)
CAS No.	124739-89-5
Molecular Formula	C8H10ClNO2
Molecular Weight	187.62 g/mol
Synonyms	5-Isopropyl-3,6-dihydro-2H-1,2-oxazine-2-carbonyl chloride; 3,6-Dihydro-5-isopropyl-2H-1,2-oxazine-2-carbonyl chloride; 5-(1-Methylethyl)-3,6-dihydro-2H-1,2-oxazine-2-carbonyl chloride; Isopropyl-dihydro-oxazine carbonyl chloride; Oxazine acid chloride intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC), tailored to meet the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request for every batch, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.