Description

3,7-Dihydroxy-7-Ethylcholanoic Acid is a high-purity synthetic bile acid derivative with significant research and development potential. This compound is valued for its defined chemical structure, which serves as a critical intermediate in the synthesis of novel pharmaceutical agents and biochemical probes. It is primarily sought by research institutions and pharmaceutical companies engaged in metabolic pathway studies, hepatology research, and the development of therapeutic agents targeting liver and digestive system disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel bile acid analogs and steroidal drugs.
• Biochemical Research: Used as a reference standard and reagent in studies of bile acid metabolism, liver function, and cholestatic diseases.
• Metabolic Pathway Analysis: Employed in in vitro and in vivo models to investigate the enterohepatic circulation and signaling pathways of bile acids.
• Drug Discovery: Serves as a precursor for developing potential therapeutics for primary biliary cholangitis (PBC), gallstones, and other hepatobiliary conditions.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry, steroid chemistry, and medicinal chemistry.

Basic Information

Product Name	3,7-Dihydroxy-7-Ethylcholanoic Acid
CAS No.	124729-57-3
Molecular Formula	C₂₆H₄₄O₄
Molecular Weight	420.63 g/mol
Synonyms	7-Ethyl-3,7-dihydroxy-5β-cholan-24-oic Acid; 7α-Ethyl-3α,7β-dihydroxy-5β-cholan-24-oic Acid; 7-Ethylchenodeoxycholic Acid; 7-ECDCA; 7-Ethyl-CDCA; 7α-Ethyl-3α,7β-dihydroxycholanoic Acid; 7-Ethyl-3,7-dihydroxycholanoic Acid
EINECS	Contact for details

Quality Control

Our 3,7-Dihydroxy-7-Ethylcholanoic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.