Description

5-Pyrimidinecarbonyl Bromide, 2-Amino- (9Ci) is a versatile and reactive pyrimidine derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in its bifunctional nature, featuring both a reactive acyl bromide group and an amino substituent, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other heterocyclic active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require a pyrimidine core structure.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Material Science Research: Acts as a monomer or cross-linking agent in the creation of functional polymers and advanced organic materials.
• Bioconjugation Chemistry: Utilized for modifying biomolecules, peptides, or proteins due to its reactive acylating capability.
• Custom Synthesis and R&D: Serves as a fundamental starting material for contract research organizations (CROs) and discovery chemistry labs exploring new chemical entities.

Basic Information

Product Name	5-Pyrimidinecarbonyl Bromide, 2-Amino- (9Ci)
CAS No.	124491-44-7
Molecular Formula	C5H4BrN3O
Molecular Weight	201.01 g/mol
Synonyms	2-Amino-5-pyrimidinecarbonyl bromide; 2-Aminopyrimidine-5-carbonyl bromide; 5-(Bromocarbonyl)-2-aminopyrimidine; 2-Amino-5-carboxypyrimidine bromide; 2-Aminopyrimidine-5-carboxylic acid bromide; 5-Carboxy-2-aminopyrimidine bromide; 2-Amino-5-pyrimidinecarboxylic acid bromide
EINECS	Contact for details

Quality Control

Every batch of 5-Pyrimidinecarbonyl Bromide, 2-Amino- (9Ci) is produced and tested under stringent quality management protocols to ensure consistency and reliability for your critical synthesis workflows. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.