Description

1-(2-(Bis-(4-Fluorophenyl)Methoxy)Ethyl)-4-(2-(4-Azido-3-Iodophenyl)Ethyl)Piperazine is a sophisticated, multi-functional organic compound designed for advanced chemical synthesis and research. This molecule is valued for its unique structural features, including fluorinated aromatic rings, an azido group, and an iodine substituent, which make it a versatile intermediate for constructing complex target molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly in areas requiring photoaffinity labeling, cross-linking, or the introduction of specific functional handles.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially for central nervous system (CNS) targets.
• Photoaffinity Labeling Probes: The azido group enables its use in creating probes for studying protein-ligand interactions and biological target identification.
• Chemical Biology Research: Utilized in bioconjugation and the synthesis of molecular tools for probing biological systems.
• Radiopharmaceutical Precursor: The iodine atom provides a potential site for radioiodination, useful in developing diagnostic imaging agents.
• Advanced Material Science: Serves as a specialized monomer or cross-linker in the synthesis of polymers with specific optical or electronic properties.
• Agrochemical Research: Used in the discovery of new active ingredients with enhanced efficacy and selectivity.

Basic Information

Item	Details
Product Name	1-(2-(Bis-(4-Fluorophenyl)Methoxy)Ethyl)-4-(2-(4-Azido-3-Iodophenyl)Ethyl)Piperazine
CAS No.	124436-31-3
Molecular Formula	C27H28F2IN5O
Molecular Weight	627.45 g/mol
Synonyms	4-[2-[4-Azido-3-iodophenyl]ethyl]-1-[2-[bis(4-fluorophenyl)methoxy]ethyl]piperazine; 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-[2-(4-azido-3-iodophenyl)ethyl]piperazine; GBR 12935 Azido Iodo Analog; GBR-12935 Photoaffinity Label; Dopamine Transporter Ligand; DAT Inhibitor Derivative
EINECS	Contact for details

Quality Control

Every batch of 1-(2-(Bis-(4-Fluorophenyl)Methoxy)Ethyl)-4-(2-(4-Azido-3-Iodophenyl)Ethyl)Piperazine is manufactured and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets the exacting standards required for research and development. Our quality protocols are designed to support cGMP and ISO guidelines where applicable, guaranteeing traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent degradation. This compound is light-sensitive and easily oxidized; prolonged exposure to light, air, or elevated temperatures should be avoided. Keep the container in a dry, well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.