Description

2-(4-(2-(2-((4-Aminophenyl)Methylcarbonylamino)Ethylaminocarbonyl)Ethyl)Phenyl)Ethylamino-5'-n-Ethylcarboxamidoadenosine CAS NO 124190-27-8 is a sophisticated adenosine derivative, a high-purity biochemical building block designed for advanced research and development. This compound is critical for its role as a potent and selective agonist for adenosine receptors, enabling precise pharmacological studies. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on cardiovascular, neurological, and inflammatory therapeutic pathways.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel adenosine receptor-targeted therapeutics.
• Biochemical Assay Development: For use in high-throughput screening (HTS) and functional assays to study adenosine receptor (A1, A2A, A2B, A3) signaling and modulation.
• Cardiovascular & Neuropharmacology Studies: Investigating its effects on heart rate, vasodilation, neuroprotection, and modulation of neurotransmitter release in preclinical models.
• Inflammation & Immunology Research: Exploring the role of adenosine signaling in immune cell regulation and the potential for developing anti-inflammatory drugs.
• Academic & Institutional Research: Serving as a critical tool compound for basic science research into purinergic signaling pathways and receptor biology.
• Process Chemistry & Scale-up: Used as a benchmark compound for developing and optimizing synthetic routes for complex nucleoside analogs.

Basic Information

Item	Details
Product Name	2-(4-(2-(2-((4-Aminophenyl)Methylcarbonylamino)Ethylaminocarbonyl)Ethyl)Phenyl)Ethylamino-5'-n-Ethylcarboxamidoadenosine
CAS No.	124190-27-8
Molecular Formula	C31H40N10O5
Molecular Weight	632.72 g/mol
Synonyms	5'-N-Ethylcarboxamidoadenosine derivative; NECA derivative; Adenosine A2 receptor agonist analog; 2-[[4-[2-[[2-[(4-Aminophenyl)methylcarbamoyl]ethyl]carbamoyl]ethyl]phenyl]ethylamino]adenosine-5'-N-ethylcarboxamide; CVT-3146 (research code); C31H40N10O5; Adenosine receptor ligand; 2-(4-(2-(2-((4-Aminophenyl)Methylcarbonylamino)Ethylaminocarbonyl)Ethyl)Phenyl)Ethylamino-NECA
EINECS	Contact for details

Quality Control

Every batch of our 2-(4-(2-(2-((4-Aminophenyl)Methylcarbonylamino)Ethylaminocarbonyl)Ethyl)Phenyl)Ethylamino-5'-n-Ethylcarboxamidoadenosine is manufactured and controlled under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards and consistent batch-to-batch purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to reach room temperature before opening to prevent condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.