Description

4,6-Diamino-2-(-D-Ribofuranosyl)-2H-Pyrazolo[3,4-D]Pyrimidine is a high-purity nucleoside analog with significant research and pharmaceutical value. This compound is a key synthetic intermediate and building block in the development of novel antiviral and anticancer therapeutics. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in medicinal chemistry and nucleotide synthesis.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of nucleoside-based antiviral and anticancer drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents targeting viral polymerases and cellular enzymes.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA synthesis pathways.
• Antiviral Agent Development: Core scaffold for creating analogs active against a range of viruses, including herpesviruses and hepatitis viruses.
• Labeled Compound Synthesis: Precursor for the preparation of isotopically labeled (e.g., 13C, 15N) nucleotides for metabolic tracing and pharmacokinetic studies.
• Academic & Institutional Research: Essential reagent for universities and research institutes exploring novel nucleoside chemistry and biology.

Basic Information

Product Name	4,6-Diamino-2-(-D-Ribofuranosyl)-2H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	124137-35-5
Molecular Formula	C10H14N6O4
Molecular Weight	282.26 g/mol
Synonyms	2-β-D-Ribofuranosyl-4,6-diaminopyrazolo[3,4-d]pyrimidine; 4,6-Diamino-2-(β-D-ribofuranosyl)pyrazolo[3,4-d]pyrimidine; 4,6-Diamino-1H-pyrazolo[3,4-d]pyrimidine riboside; 4,6-Diaminopyrazolo[3,4-d]pyrimidine ribonucleoside; NSC 680180; Pyrazolo[3,4-d]pyrimidine riboside derivative
EINECS	Contact for details

Quality Control

Our 4,6-Diamino-2-(-D-Ribofuranosyl)-2H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality control protocols suitable for research and development applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing comprehensive analytical results from HPLC, NMR, and MS are provided with every shipment to support your critical research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.