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2,2,2-Trifluoro-1-(2-Fluorophenyl)Ethanol CAS NO 124004-74-6


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CAS No.:124004-74-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,2,2-Trifluoro-1-(2-Fluorophenyl)Ethanol is a high-purity fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a trifluoroethanol and an ortho-fluorophenyl moiety, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

  • Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
  • Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and metabolic stability.
  • Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
  • Material Science Research: Employed in the creation of specialty monomers for fluorinated polymers with unique surface properties and chemical resistance.
  • Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Product Name 2,2,2-Trifluoro-1-(2-Fluorophenyl)Ethanol
CAS No. 124004-74-6
Molecular Formula C8H6F4O
Molecular Weight 194.13 g/mol
Synonyms α,α,α-Trifluoro-2-fluorobenzeneethanol; 1-(2-Fluorophenyl)-2,2,2-trifluoroethanol; 2-Fluoro-α-(trifluoromethyl)benzyl alcohol; (2-Fluorophenyl)(trifluoromethyl)methanol; 2,2,2-Trifluoro-1-(2-fluorophenyl)ethan-1-ol; 2-Fluorobenzyl alcohol, α-(trifluoromethyl)-; 2-Fluoro-α,α,α-trifluorotoluene, hydrate (reduced form)
EINECS Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(2-Fluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or solid
Identification (IR) Conforms to structure
Purity (HPLC/GC) ≥97.0% (Standard Grade)
Water Content (KF) ≤0.5%
Specific Rotation (if chiral) Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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