Description

2-Bromo-2’-Deoxyinosine is a halogenated nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial building block and a versatile intermediate in the synthesis of modified oligonucleotides and potential therapeutic agents. It is primarily utilized by researchers and manufacturers in the fields of nucleic acid chemistry, antiviral drug discovery, and molecular biology.

Application

• Oligonucleotide Synthesis: A key monomer for introducing bromine modifications into DNA strands for structural studies and probe development.
• Antiviral Research: Investigated as a precursor or analog in the development of nucleoside-based antiviral compounds.
• Biochemical Probes: Used to study enzyme mechanisms, such as those of nucleoside phosphorylases and kinases, due to its modified structure.
• Medicinal Chemistry: Serves as an important intermediate in the synthesis of novel nucleoside derivatives with potential therapeutic activity.
• Cross-coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse nucleoside libraries.
• Labeling and Diagnostics: Potential use in the creation of labeled nucleotides for diagnostic assays and imaging.

Basic Information

Product Name	2-Bromo-2’-Deoxyinosine
CAS No.	123994-87-6
Molecular Formula	C10H11BrN4O4
Molecular Weight	331.12 g/mol
Synonyms	2-Bromo-2'-deoxyinosine; 9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-bromo-1,9-dihydro-6H-purin-6-one; 2-Bromo-2'-deoxy-9H-purin-6-ol; 2-Bromo-2'-deoxyinosine (2-BrdI); 2-Bromo-deoxyinosine; 2-Br-dI; 2-Bromo-2'-deoxy-6-hydroxypurine riboside
EINECS	Contact for details

Quality Control

Our 2-Bromo-2’-Deoxyinosine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.