Description

N(2)-(3-Trifluoromethylphenyl)Guanine is a specialized guanine derivative characterized by a trifluoromethylphenyl substituent, offering unique chemical properties for advanced synthesis. This compound is significant as a high-value building block in pharmaceutical research and fine chemical manufacturing, where its structural motif is leveraged to modulate biological activity and physicochemical characteristics. It is primarily needed by research institutions and industrial developers working on nucleoside analogs, kinase inhibitors, and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel nucleoside-based antiviral or anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving purine metabolism or kinase pathways.
• Agrochemical Development: Employed in the research and synthesis of advanced active ingredients for crop protection products.
• Material Science: Acts as a functional monomer or additive in the development of specialty polymers and advanced organic materials.
• Diagnostic Reagent Synthesis: Utilized in creating labeled probes or components for diagnostic assays and imaging agents.

Basic Information

Product Name	N(2)-(3-Trifluoromethylphenyl)Guanine
CAS No.	123994-68-3
Molecular Formula	C12H8F3N5O
Molecular Weight	295.22 g/mol
Synonyms	2-Amino-1,9-dihydro-6-[(3-trifluoromethyl)phenyl]-9H-purin-6-one; 6-[(3-Trifluoromethyl)phenyl]guanine; 2-Amino-6-(3-trifluoromethylphenyl)purine; N2-(3-Trifluoromethylphenyl)guanine; Guanine, N-(3-trifluoromethylphenyl)-; 9H-Purin-6-amine, 2-amino-9-[(3-trifluoromethyl)phenyl]- (CAS alternative listing)
EINECS	Contact for details

Quality Control

Our N(2)-(3-Trifluoromethylphenyl)Guanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.