Description

Cyclohexanecarbonyl Chloride, 4-Methoxy-, trans- (9Ci) is a specialized chiral acyl chloride derivative, a crucial building block in advanced organic synthesis. Its value lies in its ability to introduce the trans-4-methoxycyclohexanecarbonyl moiety, a structural motif of significant interest in medicinal chemistry. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific stereochemical requirements.
• Chiral Auxiliary/Resolving Agent Precursor: Serves as a starting material for creating chiral reagents used in asymmetric synthesis.
• Liquid Crystal & Advanced Material Research: Employed in the development of organic electronic materials and liquid crystal compounds due to its rigid, substituted cyclohexane core.
• Peptide & Protein Modification: Acts as an acylating agent for modifying amino acids or peptides to study structure-activity relationships.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical suppliers offering bespoke synthesis services for clients in R&D.

Basic Information

Product Name	Cyclohexanecarbonyl Chloride, 4-Methoxy-, trans- (9Ci)
CAS No.	123790-13-6
Molecular Formula	C8H13ClO2
Molecular Weight	176.64 g/mol
Synonyms	trans-4-Methoxycyclohexanecarbonyl Chloride; (trans)-4-Methoxycyclohexanecarboxylic Acid Chloride; 4-Methoxycyclohexanecarboxylic Acid Chloride, trans-; p-Methoxycyclohexanecarbonyl Chloride, trans-; 1-(Chlorocarbonyl)-4-methoxycyclohexane, trans-; 4-Methoxycyclohexanoyl Chloride, trans-
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanecarbonyl Chloride, 4-Methoxy-, trans- (9Ci) is manufactured and tested under strict quality management protocols to ensure high chemical purity and stereochemical integrity. Our products undergo rigorous quality testing, including chiral HPLC analysis, to ensure compliance with industry standards for advanced intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (trans-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.