Description

5'-o-Benzoyl-2'-Deoxyuridine is a protected nucleoside derivative, a crucial intermediate in the synthesis of modified oligonucleotides and therapeutic nucleic acids. This compound is essential for researchers and manufacturers requiring high-purity building blocks for advanced pharmaceutical development, particularly in the fields of antisense therapy and diagnostic probes. It is primarily utilized by biotechnology firms, pharmaceutical R&D laboratories, and fine chemical suppliers serving the global life sciences market.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used as a protected monomer in solid-phase synthesis for research and therapeutic oligonucleotides.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to DNA metabolism and repair.
• Prodrug Development: Employed in the design of prodrugs to enhance the bioavailability and targeting of nucleoside-based therapeutics.
• Diagnostic Probe Manufacture: Integral component in creating labeled probes for genetic testing and molecular diagnostics.
• Academic & Contract Research: Fundamental reagent for universities and CROs conducting studies in medicinal chemistry and molecular biology.

Basic Information

Product Name	5'-o-Benzoyl-2'-Deoxyuridine
CAS No.	123606-62-2
Molecular Formula	C16H16N2O6
Molecular Weight	332.31 g/mol
Synonyms	2'-Deoxy-5'-O-benzoyluridine; 5'-O-Benzoyl-2'-deoxyuridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-benzoyloxy-pyrimidine-2,4-dione; 2'-Deoxyuridine, 5'-benzoate; Uridine, 2'-deoxy-, 5'-benzoate
EINECS	Contact for details

Quality Control

Our 5'-o-Benzoyl-2'-Deoxyuridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.