Description

7-Methyl-2'-Deoxyguanosine 3'-Monophosphate is a modified nucleoside monophosphate crucial for advanced biochemical research and pharmaceutical development. This compound serves as a vital building block and reference standard in the study of DNA damage, repair mechanisms, and epigenetic modifications. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in oncology research, biomarker discovery, and the synthesis of novel nucleotide analogs.

Application

• Biochemical Research: Used as a critical substrate or standard in studies of DNA alkylation damage, repair pathways, and mutagenesis.
• Diagnostic Development: Serves as a reference material in the calibration and development of diagnostic assays for detecting specific DNA lesions or biomarkers.
• Pharmaceutical R&D: Employed as a key intermediate in the research and synthesis of novel nucleoside-based therapeutics, including potential antiviral or anticancer agents.
• Epigenetics Studies: Acts as a tool compound for investigating the role of modified DNA bases in epigenetic regulation and gene expression.
• Analytical Standard: Provides a high-purity standard for analytical methods such as HPLC, LC-MS, and capillary electrophoresis in quality control and metabolomics.

Basic Information

Item	Detail
Product Name	7-Methyl-2'-Deoxyguanosine 3'-Monophosphate
CAS No.	123497-14-3
Molecular Formula	C11H16N5O7P
Molecular Weight	361.25 g/mol
Synonyms	7-Methyl-dGMP; 7-Methyl-2'-deoxyguanosine 3'-(dihydrogen phosphate); 2'-Deoxy-7-methylguanosine 3'-monophosphate; 7-Methyl-2'-deoxy-GMP; 7-Me-dGMP; 3'-dGMP-7-Me; 7-Methyl-deoxyguanylic acid; N7-Methyl-2'-deoxyguanosine 3'-monophosphate
EINECS	Contact for details

Quality Control

Our 7-Methyl-2'-Deoxyguanosine 3'-Monophosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (UV)	Spectrum corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.