Description

1H-Imidazole-5-Carbonyl Chloride, 1-Propyl- (9Ci) is a specialized organic intermediate featuring a reactive carbonyl chloride group on an imidazole ring, making it a valuable building block for complex synthesis. This compound is critical for introducing the imidazole pharmacophore into target molecules, enabling the development of compounds with specific biological activity. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the imidazole moiety is essential.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of advanced polymers and functional materials with unique electronic or binding properties.
• Bioconjugation and Probe Synthesis: The reactive acid chloride group allows for coupling to amines, useful in creating biochemical probes and labeled compounds.

Basic Information

Product Name	1H-Imidazole-5-Carbonyl Chloride, 1-Propyl- (9Ci)
CAS No.	123451-28-5
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	1-Propyl-1H-imidazole-5-carbonyl chloride; 1-Propylimidazole-5-carbonyl chloride; 5-(Chlorocarbonyl)-1-propylimidazole; 1-Propyl-1H-imidazole-5-carboxylic acid chloride; Propylimidazole carbonyl chloride; 1-n-Propylimidazole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-5-Carbonyl Chloride, 1-Propyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.