Description

1H-Imidazole-5-Carbonyl Chloride, 1-Butyl- (9Ci) is a specialized, high-value chemical intermediate belonging to the imidazole class, characterized by its reactive carbonyl chloride functional group. This compound is critical for introducing the 1-butylimidazole moiety into complex molecular architectures, enabling the synthesis of advanced materials and active pharmaceutical ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the imidazole scaffold is pharmacologically active.
• Agrochemical Synthesis: Used in the research and development of new fungicides, herbicides, and plant growth regulators that incorporate heterocyclic structures.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized N-heterocyclic carbene (NHC) ligands and other organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers, ionic liquids, and metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or affinity probes for studying biological pathways and protein interactions.

Basic Information

Product Name	1H-Imidazole-5-Carbonyl Chloride, 1-Butyl- (9Ci)
CAS No.	123451-26-3
Molecular Formula	C8H11ClN2O
Molecular Weight	186.64 g/mol
Synonyms	1-Butyl-1H-imidazole-5-carbonyl chloride; 1-Butylimidazole-5-carbonyl chloride; 5-(Chlorocarbonyl)-1-butylimidazole; 1-Butyl-5-imidazolecarbonyl chloride; 1-Butyl-1H-imidazole-5-carboxylic acid chloride; Butylimidazole carbonyl chloride; N-Butylimidazole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 1H-Imidazole-5-Carbonyl Chloride, 1-Butyl- (9Ci) is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive analytical data including HPLC purity, NMR, and IR spectroscopy for identity confirmation. A detailed Certificate of Analysis (COA) is supplied with each shipment, and we support custom purity requirements for advanced research and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.