Description

n-(4-Azido-2-Nitrobenzoyl)-1,7-Diaminoheptane is a specialized bifunctional chemical compound featuring both a photoreactive azido group and a reactive amine terminus. This unique structure makes it a valuable heterobifunctional crosslinking agent for photoaffinity labeling and bioconjugation applications in advanced research and development. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and life science sectors for probing protein interactions, developing diagnostic assays, and creating novel biomaterials.

Application

• Photoaffinity Labeling Probe: Used to covalently tag and identify biological targets, such as proteins and receptors, upon UV light activation.
• Bioconjugation & Linker Chemistry: Serves as a heterobifunctional crosslinker for coupling biomolecules (e.g., peptides, antibodies, oligonucleotides) to surfaces, polymers, or other molecules.
• Proteomics Research: A key reagent for studying protein-protein interactions, ligand binding sites, and mapping active sites in enzymes.
• Diagnostic Assay Development: Employed in the fabrication of biosensors and immunoassays where stable, light-induced immobilization is required.
• Material Science: Used to functionalize polymers and nanomaterials with bioactive ligands for targeted drug delivery systems or tissue engineering scaffolds.
• Chemical Biology Tool: Facilitates the study of metabolic pathways and cellular processes through the introduction of photo-reactive tags.

Basic Information

Product Name	n-(4-Azido-2-Nitrobenzoyl)-1,7-Diaminoheptane
CAS No.	123402-80-2
Molecular Formula	C14H20N6O3
Molecular Weight	320.35 g/mol
Synonyms	1,7-Heptanediamine, N-(4-azido-2-nitrobenzoyl)-; 4-Azido-2-nitrobenzoic acid N-(7-aminoheptyl)amide; ANB-HA; ANB-heptylamine; Heterobifunctional Crosslinker ANB-HA; Photo-reactive crosslinker; N-(4-Azido-2-nitrobenzoyl)-1,7-diaminoheptane; N-(7-Aminoheptyl)-4-azido-2-nitrobenzamide
EINECS	Contact for details

Quality Control

Our production of n-(4-Azido-2-Nitrobenzoyl)-1,7-Diaminoheptane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive research applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. For long-term storage under inert atmosphere, consider storing desiccated at -20°C. This compound is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Residue on Ignition	≤ 0.5 %
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.