Description

3'-Fluoro-3'-Deoxycytidine is a fluorinated nucleoside analog, a key building block in medicinal chemistry and life science research. This compound is valued for its role as a modified cytidine derivative, enabling the study of nucleic acid interactions and serving as a precursor for antiviral and anticancer prodrug development. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on nucleoside chemistry and antiviral therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate polymerase activity and nucleic acid metabolism.
• Pro-drug Development: Serves as a key scaffold for developing fluorinated pro-drugs with enhanced metabolic stability and bioavailability.
• Antiviral Agent Synthesis: Employed in the research and development of potential therapeutic agents targeting viral replication.
• Life Science Tool: Utilized in molecular biology and diagnostic assay development as a modified nucleotide.
• Chemical Biology Probes: Acts as a building block for creating probes to study cellular processes and gene function.

Basic Information

Product Name	3'-Fluoro-3'-Deoxycytidine
CAS No.	123402-20-0
Molecular Formula	C9H12FN3O4
Molecular Weight	245.21 g/mol
Synonyms	3'-Fluoro-3'-deoxycytidine; 2(1H)-Pyrimidinone, 4-amino-1-[5-fluoro-5-(hydroxymethyl)-2-tetrahydrofuranyl]-; 4-Amino-1-(5-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 3'-F-3'-dCyd; 3'-Fluoro-2'-deoxycytidine (common misnomer); 5-Fluoro-5-(hydroxymethyl)-1-(4-amino-2-oxopyrimidin-1-yl)tetrahydrofuran; FCyd
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-3'-Deoxycytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.